Antabuse Description

2009-05-03T17:18:00.000-07:00

Antabuse (also known as disulfiram) was the first drug to be approved by the U.S. Food and Drug Administration for treatment of alcohol dependence. The main trait of antabuse pills is that they cause negative effects on the imbiber when he\she consumes alcohol. The human metabolism is built that way that when alcohol is consumed, it is being recycled into acetaldehyde, which causes most of the hangover symptoms. Acetaldehyde is then metabolised into acetic acid, which is completely harmless. What antabuse does, it stops the acetaldehyde oxidation process, thus preventing it from turning into acetic acid. The result is a buildup of the toxic acetaldehyde in the organism, which eventually causes 10 or more times stronger symptoms then those of a heavy drinker with hangover.

Side Effects

The effects from taking both antabuse and alcohol range widely from mild to severe, depending on the amount of consumed substance, and drug dosage.
When you drink while taking antabuse, the following symptoms may occur:
Flushing, weakness, hyperventilation, respiratory difficulty, throbbing in the head and neck, tachycardia, chest pain, confusion, sweating, nausea, copious vomiting, thirst, palpitations, throbbing headache, hypotension, vertigo, blurred vision, overall uneasiness.
Mentioned above are the mild antabuse symptoms. Severe drug reactions include, but not limited to respiratory depression, myocardial infarction, cardiovascular collapse, acute congestive heart failure, unconsciousness, arrhythmias, convulsions, and even death.

Restrictions

Due to the severe side effects of antabuse, only those who absolutely want to quit drinking and are fully aware of the consequences of drinking while on antabuse medication should take antabuse pills, it should never be given to someone without providing full knowledge about the drug and its side effects. Because of high possible of violent body reactions, antabuse by all means must not be given to anyone with a background of severe heart disease, allergy or mental illnesses. Pregnant women are not advised to take antabuse treatment. Also, people taking paraldehyde or metronidazole should not use antabuse to avoid drug interference.

Antabuse Effectiveness

Since antabuse serves only as physical and psychological backup to someone trying to stop drinking, it does not actually have any metabolic effect, like reducing one craving for alcohol, nor does antabuse reduce or treat any alcohol withdrawal symptoms. The effectiveness of Antabuse medication depends on the person’s determination to stop drinking and carry on with the treatment. A person who quit the treatment might turn back into a drinker after a day or two, after the metabolic cycle is finished and the negative effects fade, that’s why it is essential to take the pills on time and keep up with the schedule. The latest research results reveal that after the full antabuse treatment course is taken, over 50% of patients quit drinking, and further medicine administration helps them develop a strong dislike to alcohol, as not to start drinking again.

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Full Antabuse Description and History

Antabuse Description